FIGURE

Figure 10

ID
ZDB-FIG-200226-11
Publication
Liu et al., 2020 - The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling
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Figure 10

A proposed mechanism of 4-HPPP-induced antiproliferation and apoptosis in NSCLC cells through modulating the signaling of endogenous antioxidant systems, such as SOD2 and PRX1, causing DNA damage and high-grade aneuploidy. Eventually, the accumulation of DNA damage and hyperaneuploidization induce apoptosis in NSCLC cells.

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Antibody Labeling
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Phenotype Detail
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