FIGURE

Figure 4

ID

ZDB-FIG-200101-30

Publication

Murat El Houdigui et al., 2019 - A systems biology approach reveals neuronal and muscle developmental defects after chronic exposure to ionising radiation in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Figure 4

(a) Number of transcription factors (TF) with significant deregulation (|fold change| ≥ 1.5 and adjusted p-value < 0.01) over developmental time at three different dose rates. (b) Hierarchical clustering of 462 TF misregulated in at least one comparative analysis. Blue indicate downregulation, white no change and red upregulation, as compared to control conditions. Clusters of co-regulated genes are indicated at the right from 1 to 6. (c) GO enrichment of TF classified in 6 different clusters. Cluster number are indicated below, the total number of deregulated TF in each GO term in brackets. (d) Expression patterns (as normalised count) of key master regulators during development using loess smoothed conditional means. Cluster numbers are indicated at the top. *|fold change| ≥ 1.5 and adjusted p-value < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.