Figure 1—figure supplement 2.

LY-411575 and cyclopamine are efficient inhibitors of Notch and Hh signalling, respectively.

Wild-type embryos were treated with LY-411575 or cyclopamine for 0, 1, 2, 4, 6, 8, or 10 hr, and fixed at 24 hpf. Whole mount in situ hybridisation was then performed for her12 in LY-411575 treated embryos and ptc2 in cyclopamine treated embryos. Brackets denote the extent of the spinal cord. n = 15 embryos per staining. Scale bar: 20 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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