FIGURE

Fig. 4

ID

ZDB-FIG-190913-70

Publication

Toms et al., 2019 - Phagosomal and mitochondrial alterations in RPE may contribute to KCNJ13 retinopathy

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Increased mitochondrial size in the retinal pigment epithelium (RPE) of obe^td15 zebrafish. Mitochondrial size in the wild-type (WT) RPE at (a) 3 months post-fertilisation (mpf), (c) 6 mpf and (e) 12 mpf shows a decrease with age, while mitochondrial size in the obe^td15 RPE at (b) 3 mpf, (d) 6 mpf and (f) 12 mpf shows an increase with age. Mitochondrial area measured from TEM images displayed on bar chart (g). Results are mean ± SEM. 13 mitochondria measured per WT and mutant age group. Statistical significance relative to WT of different ages ^†p < 0.05, ^††p < 0.01. Statistical significance relative to WT against obe^td15 of the same age. ***p < 0.001. Scale bar = 200 nm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kcnj13^td15/td15
Observed In:	retinal pigmented epithelium mitochondrion
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.