FIGURE

Figure 1

ID
ZDB-FIG-190723-68
Publication
Liebscher et al., 2015 - How to wake a giant
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Figure 1

Activation mechanism of aGPCRs

AGPCRs are gigantic molecules that share characteristic features as a GPCR autoproteolysis inducing (GAIN) domain which harbors the GPCR proteolytic site (GPS), at which the receptor is cleaved into an N-terminal (NTF) and a C-terminal fragment (CTF). A tethered peptide agonist called the Stachel sequence (red) or derived peptides activate the receptor.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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