FIGURE

Fig. 2

ID
ZDB-FIG-190625-8
Publication
Pacentine et al., 2019 - Subunits of the mechano-electrical transduction channel, Tmc1/2b, require Tmie to localize in zebrafish sensory hair cells
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Fig. 2

Tmie-GFP is present in the hair bundles of MET mutants.

Confocal images of the bundle region in hair cells of the inner ear lateral cristae in 6 dpf larvae. Larvae expressing transgenic Tmie-GFP in the genetic backgrounds of wild type (A), and homozygous mutants for the tip link protein Pcdh15a (B, pcdh15apsi7), the accessory protein Lhfpl5a (C, lhfpl5atm290d), and the Golgi-localized protein Tomt (D, tomttk256c). Tomt-deficient fish lack Tmc expression in hair cell bundles [11], presumably mimicking the condition of a triple Tmc knockout. Arrowheads indicate splayed hair bundles. n = 8 each genotype. Scale bar is 5μm.

Expression Data
Gene:
Fish:
Anatomical Term:
Stage: Day 6

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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