FIGURE

Fig. S6

ID

ZDB-FIG-190620-24

Publication

Cau et al., 2019 - A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification

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Fig. S6

Alteration of Notch activity modifies the expression of the Tg(BMPRE-AAV.Mlp:d2EGFP)^mw30transgene. (A-B) Confocal projections of WT and Tg(hsp70l:dnXla.Rbpj-MYC)^vu21 (Notch KD) embryos at 22 hpf. Embryos are shown in dorsal views. The Tg(BMPRE-AAV.Mlp:d2EGFP)^mw30 transgene (BRE:d2EGFP) is shown in green. Scale bar is 15 μm. (C) Counts of dGFP+ cells in WT and Tg(hsp70l:dnXla.Rbpj-MYC)^vu21 (Notch KD) embryos at 23 hpf. Underlying data can be found in S2 Data. Heat shock was performed at 14 hpf. Error bars represent SD. *p < 0.05 using a t test. Underlying data can be found in S2 Data. D2EGFP, destabilized enhanced green fluorescent protein; KD, knock-down; hpf, hours post fertilization; WT, wild-type.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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