FIGURE

Fig. 8

ID

ZDB-FIG-190307-14

Publication

Hsieh et al., 2018 - Pparα deficiency inhibits the proliferation of neuronal and glial precursors in the zebrafish central nervous system

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Fig. 8

Pparαa or Pparαb alone is not sufficient to rescue the GW6471‐treatment phenotype. In situ hybridization and quantitative real‐time polymerase chain reaction demonstrating that injection of either zebrafish pparaa or pparab coding sequence could not rescue the downregulation of neuronal and glial markers caused by GW6471. In contrast, coinjection of pparaa and pparab rescued the neuronal and glial defects caused by GW6471. **P < 0.01; ***P < 0.001. Staging of the embryos is shown in the bottom left corner of each panel.

Expression Data

Genes:	ascl1b gfap neurog1 slc1a3a
Fish:	TU
Condition:	chemical treatment by environment: GW 6471
Anatomical Terms:	glioblast neural plate neuroblast (sensu Vertebrata) whole organism
Stage Range:	Bud to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU
Condition:	chemical treatment by environment: GW 6471
Observed In:	glioblast neural plate neuroblast (sensu Vertebrata) whole organism
Stage Range:	Bud to Prim-5

Phenotype Detail

Acknowledgments

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