Gene

slc1a3a

ID
ZDB-GENE-030131-2159
Name
solute carrier family 1 member 3a
Symbol
slc1a3a Nomenclature History
Previous Names
  • slc1a3 (1)
  • EAAT1A (1)
  • glasta (1)
  • wu:fb98e05
  • wu:fd50b05
  • zgc:56661
  • zgc:77768
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in D-aspartate import across plasma membrane; L-aspartate import across plasma membrane; and L-glutamate import across plasma membrane. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including glioblast; liver; nervous system; neural tube; and radial glial cell. Human ortholog(s) of this gene implicated in episodic ataxia type 6. Orthologous to human SLC1A3 (solute carrier family 1 member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc1a3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
episodic ataxia type 6 Alliance Episodic ataxia, type 6 612656
Associated With slc1a3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018107 Sodium:dicarboxylate symporter, conserved site
Family IPR001991 Sodium:dicarboxylate symporter
Homologous_superfamily IPR036458 Sodium:dicarboxylate symporter superfamily
Domain Details Per Protein
Protein Length Sodium:dicarboxylate symporter Sodium:dicarboxylate symporter, conserved site Sodium:dicarboxylate symporter superfamily
UniProtKB:Q6P4V2 537
UniProtKB:Q7ZUB7 537
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations