FIGURE

Fig. 7-S2

ID
ZDB-FIG-181025-13
Publication
Row et al., 2018 - BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity
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Fig. 7-S2

Over-expression of msgn1 rescues id3 over-expression.

HS:id3 and HS:msgn1 lines were crossed to each other and heat-shocked at the 12-somite stage and fixed at 24 hpf for analysis of myod and kdrl expression. The activation of msgn1 alone results in relatively normal myod expression and a posterior loss of kdrl. Activation of id3 causes a strong loss of posterior myod expression and gain of kdrl expression throughout regions where somites normally form. Activation of id3 and msgn1 largely restores normal patterning of muscle and vasculature.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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