FIGURE

Fig. S3

ID
ZDB-FIG-180827-11
Publication
Addison et al., 2018 - Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain
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Fig. S3

cyp26c1 mutant embryos have ectopic egr2-expressing cells

(A-D): Expression of egr2 was analyzed in cyp26c1 mutant embryos. Ectopic egr2-expressing cells were observed in r2 and r4 (arrowheads), as seen in morphants (Fig.6B). That this phenotype occurs following inactivation of cyp26c1 alone suggests that RA levels in r2 and r4 are altered sufficiently to disrupt identity switching. Scale bar: 50 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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Reprinted from Developmental Cell, 45, Addison, M., Xu, Q., Cayuso, J., Wilkinson, D.G., Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain, 606-620.e3, Copyright (2018) with permission from Elsevier. Full text @ Dev. Cell