FIGURE

Fig. 3

ID
ZDB-FIG-180712-81
Publication
Kelu et al., 2018 - TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons.
Other Figures
All Figure Page
Back to All Figure Page
Fig. 3

Effect of depleting the acidic Ca2+ stores and antagonizing TPCs on the spontaneous Ca2+ activity of the CaPs in SAIGFF213A;UAS:GCaMP7a embryos at ~18 hpf and ~24 hpf. Embryos were (A, B) untreated, or (C-H) they were treated with: (C,D) 1% DMSO, (E,F) 1 µM bafilomycin A1, or (G, H) 250 µM trans-ned-19. Drug treatments started at ~ 17 hpf, and finished at either (A,C,E,G) ~ 18 hpf or (B,D,F,H) ~ 24 hpf. (Ai-Hiv) Time-lapse fluorescence images, and (Av-Hv) line graphs as described in Fig. 1.

Expression Data
Gene:
Fish:
Conditions:
Anatomical Term:
Stage Range: 14-19 somites to Prim-5

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Conditions:
Observed In:
Stage: Prim-5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 438(1), Kelu, J.J., Webb, S.E., Galione, A., Miller, A.L., TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons., 57-68, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.