FIGURE

Fig. S5

ID

ZDB-FIG-180629-8

Publication

Morrice et al., 2018 - Modeling Environmentally-Induced Motor Neuron Degeneration in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. S5

Microglial engulfment of apoptotic neurons at 72 hpf.

Representative static images from live imaging of a microglial cell engulfing an apoptotic neuron in the spinal cord at 72 hpf following BPA exposure in a double transgenic Tg:pU1:Gal4-UAS-RFP/NBT:DLexPR-secA5-TagBFP embryo, which have pU1+ microglia cells labeled in red and apoptotic neurons labeled in blue. Asterisks denotes pU1+ cell (in red) in the process of engulfing a neuron undergoing apoptosis (in blue) in the spinal cord and its subsequent migration away from this site. White arrow denotes an apoptotic neuron being removed from the spinal cord over a time course of 20 minutes. Note that specific microglia were not followed from 48 hpf to 72 hpf, and cells imaged in this figure illustrate the general microglial response in the spinal cord at 72 hpf. Images were collected from N = 1 biological replicate.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.