|ZFIN ID: ZDB-FIG-180620-41|
Embryos injected with α4a-SMO1 and the α4aR278Q mutant embryos fail to exhibit correct escape behavior. (A) Wild-type (control) fish responds to touch by with a C-bend, a turn away from the stimulus and rapid swimming. However, embryos injected with α4a-SMO1 (B) or with mRNA for the GlyR α4aR278Q subunit (C) respond more slowly, and have a pronounced head retraction—similar to a localized beo-like contraction (arrow). Single images were extracted from high-speed movies of α4a-SMO1 morphants and embryos injected with GlyR α4aR278Q subunit mRNA.
|WT + MO3-glra4a||standard conditions||Long-pec||startle response disrupted, abnormal|
|Long-pec||thigmotaxis disrupted, abnormal|
|Acknowledgments:||This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.|