FIGURE

Fig. 4

ID

ZDB-FIG-180522-29

Publication

Duong et al., 2017 - Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms

Other Figures

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Fig. 4

Nr2f1a functions upstream of Bmp signaling to restrict ECs. (A-D) IHC of hearts from myl7: DsRed-NLS WT, nr2f1a mutant, WT DM-treated, and nr2f1a mutant DM-treated embryos for Alcama (green) and DsRed (myocardial nuclei – red). Images are frontal views of confocal stacks. Length of ECs (arrowheads). Individual EC cells (asterisks). Scale bar indicates 10 µm in A-D. (E) Mean EC number from inferior and superior valve sides in WT (n = 12), nr2f1a mutant (n = 9), WT DM-treated (n = 11), and nr2f1a mutant DM-treated (n = 13) embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nr2f1a^el512/el512; f2Tg
Condition:	chemical treatment by environment: dorsomorphin
Observed In:	atrioventricular canal endocardial cushion cell
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 434(1), Duong, T.B., Ravisankar, P., Song, Y.C., Gafranek, J.T., Rydeen, A.B., Dohn, T.E., Barske, L.A., Crump, J.G., Waxman, J.S., Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms, 7-14, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.