FIGURE

Fig. 1

ID

ZDB-FIG-180418-16

Publication

Sarmah et al., 2017 - Embryonic Ethanol Exposure Affects Early- and Late-Added Cardiac Precursors and Produces Long-Lasting Heart Chamber Defects in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Ethanol-induced cardiac chamber defects occurring during embryogenesis persisted in older zebrafish larvae. (A?C) 3D renderings of confocal sections of Tg(kdrl:EGFP) show closely attached atrium and ventricle residing side by side in the control larva (A); ventricles are on the top of the atria in ethanol-exposed larvae (B,C); Dotted yellow line represents the line through AV valves connecting atrium and ventricle. The angle between yellow line and antero-posterior axis is shown by white dots; (D?F) Masson?s trichrome stained histology sections at the atrioventricular canal region showing both atrium and ventricle revealed defective anatomy of the ethanol-exposed larvae (E,F) compared to control (D); (G?I) Masson?s trichrome stained histology sections of the ventricle showed healthy looking cardiac muscle (red colored trabeculae) in control larva (G); and myocardial damage (blue colored trabeculae, yellow arrows) in ethanol-exposed larvae (H,I).

Expression Data

Gene:	GFP
Fish:	la116Tg
Condition:	chemical treatment by environment: ethanol
Anatomical Term:	heart
Stage:	Days 14-20

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT la116Tg
Condition:	chemical treatment by environment: ethanol
Observed In:	atrioventricular valve atrium cardiac ventricle heart trabecular layer Collagen
Stage:	Days 14-20

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Toxics