ZFIN ID: ZDB-FIG-171226-16
Tyrkalska et al., 2016 - Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins. Nature communications   7:12077 Full text @ Nat. Commun.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Days 7-13

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
gbp4 sh267Tg; ums2Tg control Protruding-mouth whole organism RTPCR
sh267Tg; ums3Tg control Long-pec whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium Long-pec - Days 7-13 whole organism decreased life span, abnormal
Protruding-mouth cysteine-type endopeptidase activity involved in apoptotic process increased occurrence, abnormal
WT + MO1-cxcr2 bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium Long-pec - Days 7-13 whole organism decreased life span, exacerbated
WT + MO1-gbp4 bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium Long-pec - Days 7-13 whole organism decreased life span, exacerbated
sh267Tg; ums2Tg control Protruding-mouth whole organism gbp4 expression increased amount, abnormal
sh267Tg; ums2Tg bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium Long-pec - Days 7-13 whole organism decreased life span, ameliorated
Protruding-mouth cysteine-type endopeptidase activity involved in apoptotic process increased occurrence, exacerbated
sh267Tg; ums2Tg + MO1-gbp4 bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium Long-pec - Days 7-13 whole organism decreased life span, ameliorated
sh267Tg; ums3Tg control Long-pec whole organism gbp4 expression increased amount, abnormal
sh267Tg; ums3Tg bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium Long-pec - Days 7-13 whole organism decreased life span, exacerbated
Protruding-mouth cysteine-type endopeptidase activity involved in apoptotic process occurrence, ameliorated
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.