FIGURE

Fig. S8

ID
ZDB-FIG-170825-1
Publication
Tyrkalska et al., 2016 - Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins
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Fig. S8

Gbp4 regulates the number of neutrophils.

Zebrafish mpx:eGFP one-cell embryos were injected with standard control (Std) or Gbp4 MOs in combination with antisense (As), Gbp4 (A-E) or Gcsfa (C-E) mRNAs (A, D). Each dot represents the number of neutrophils from a single larva, while the mean ± SEM for each group is also shown. The sample size (n) is indicated for each treatment. (C) At 2 dpf, larvae were infected and survival determined as described in Figures 2A. (B, E) Representative images of green channels of whole larvae for the different treatments. Scale bars, 100 μm. The sample size for each treatment is shown in the graph in A and D, and is 290 in C . ns, not significant; ***p<0.001 according to log rank test (C) or ANOVA followed by Tukey multiple range test (A and D).

Expression Data
Gene:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Knockdown Reagent:
Observed In:
Stage Range: Long-pec to Days 7-13

Phenotype Detail
Acknowledgments
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