FIGURE

Fig. 4

ID
ZDB-FIG-171113-37
Publication
de Boeck et al., 2016 - Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model
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Fig. 4

Smad6 knockdown results in reduced cell invasion of MDA-MB-231 cells.

(a) Quantitative PCR (qPCR) analysis of Smad6 mRNA expression in MDA-MB-231 cells infected with control vector, non-targeting shRNA and two Smad6 shRNA constructs, respectively. (b) Quantification of invasive cell numbers in vector control, non-targeting control and Smad6 knockdown MDA-MB-231 cells injected zebrafish larvae. (c) Representative images of 6 dpi zebrafish larvae showing the Smad6 knockdown effect in MDA-MB-231 cell invasion. Scale bar: μm. 100 *0.01 < P < 0.05.

Expression Data
Gene:
Fish:
Condition:
Anatomical Term:
Stage: Days 7-13

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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