ZFIN Figure: Boyd et al., 2017, Fig. 2

ZFIN ID: ZDB-FIG-170802-1

ZFIN ID: ZDB-FIG-170802-1

Boyd et al., 2017 - Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy. PLoS Genetics 13:e1006744 Full text @ PLoS Genet.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Antibody:	Ab2-atp5a
Fish:	WT WT + MO1-smn1
Knockdown Reagent:	MO1-smn1
Anatomical Term:	whole organism
Stage:	Long-pec

PHENOTYPE:

Fish:	WT + MO1-smn1
Knockdown Reagent:	MO1-smn1
Observed In:	whole organism whole organism aerobic respiration whole organism mitochondrion whole organism obsolete ATP generation from ADP
Stage Range:	Prim-5 to Long-pec

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details

Antibody	Assay	Fish	Conditions	Stage	Anatomy
Ab2-atp5a	WB	WT	standard conditions	Long-pec	whole organism
	WB	WT + MO1-smn1	standard conditions	Long-pec	whole organism

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT + MO1-smn1	standard conditions	Prim-5	whole organism aerobic respiration decreased efficacy, abnormal
		Prim-5	whole organism mitochondrion decreased functionality, abnormal
		Prim-5	whole organism obsolete ATP generation from ADP decreased efficacy, abnormal
		Long-pec	whole organism Ab2-atp5a labeling decreased amount, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.