HUMAN DISEASE MODELED by WT + MO1-smn1

Human Disease	Conditions	Citations
spinal muscular atrophy	standard conditions	(4)

GENE EXPRESSION
Gene expression in WT + MO1-smn1

PHENOTYPE
Phenotype in WT + MO1-smn1

Phenotype	Conditions	Figures
axon extension process quality, abnormal	standard conditions	Fig. 7  from Chitramuthu et al., 2010
axonogenesis disrupted, abnormal	standard conditions	Fig. 4 from Oprea et al., 2008
CaP motoneuron axon branched, abnormal	standard conditions	Fig. 4 from See et al., 2014 Fig. 7  from Chitramuthu et al., 2010
CaP motoneuron axon decreased length, abnormal	standard conditions	Fig. 7  from Chitramuthu et al., 2010
CaP motoneuron axon truncated, abnormal	standard conditions	Fig. 4 from See et al., 2014
motor neuron axon branchiness, abnormal	standard conditions	Fig. 5 from Winkler et al., 2005
motor neuron axon morphology, abnormal	standard conditions	Fig. 4 from Oprea et al., 2008
motor neuron axon truncated, abnormal	standard conditions	Fig. 5 from Winkler et al., 2005
mRNA splicing, via spliceosome decreased process quality, abnormal	standard conditions	Fig. 2 from See et al., 2014
primary motor neuron axon decreased length, abnormal	standard conditions	Fig. 5  from Boyd et al., 2017
primary motor neuron axon terminus swollen, abnormal	standard conditions	Fig. 5  from Boyd et al., 2017
primary motor neuron axonogenesis disrupted, abnormal	standard conditions	Fig. 5  from Boyd et al., 2017
whole organism Ab2-atp5a labeling decreased amount, abnormal	standard conditions	Fig. 2 from Boyd et al., 2017
whole organism aerobic respiration decreased efficacy, abnormal	standard conditions	Fig. 2 from Boyd et al., 2017
whole organism ATP generation from ADP decreased efficacy, abnormal	standard conditions	Fig. 2 from Boyd et al., 2017
whole organism mitochondrion decreased functionality, abnormal	standard conditions	Fig. 2 from Boyd et al., 2017