FIGURE

Fig. S3

ID

ZDB-FIG-170210-15

Publication

Kiando et al., 2016 - PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance

Other Figures

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Fig. S3

Phenotypic evaluation of phactr1 knockdown zebrafish.

(A) RT-PCR evaluation of splice alteration observed following microinjection of phactr1 morpholino (PHACTR1 KD). (B) Brightfield micrographs of overt morphology at 60 hours post fertilization. (C) Two-dimensional projections obtained from z-series confocal images in the head and trunk of control and phactr1 knockdown zebrafish embryos. Green represents the vascular endothelium as marked by EGFP. Greyscale represents the corresponding DIC brightfield image of the fish head and trunk region. HPV indicates the relative position of the developing hepatic portal vein

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB/TU + MO1-phactr1 s843Tg + MO1-phactr1
Knockdown Reagent:	MO1-phactr1
Observed In:	hepatic portal vein trunk intersegmental vessel whole organism
Stage Range:	Pec-fin to Protruding-mouth

Phenotype Detail

Acknowledgments

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