FIGURE

Fig. 7

ID

ZDB-FIG-161222-18

Publication

Lau et al., 2016 - Knockout of Zebrafish Ovarian Aromatase Gene (cyp19a1a) by TALEN and CRISPR/Cas9 Leads to All-male Offspring Due to Failed Ovarian Differentiation

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Fig. 7

Gonad development at 40 dpf in the control (cyp19a1a^+/−; fish A–D) and mutant (cyp19a1a^−/−; fish E–L). The control fish had well-differentiated ovary (A and B) and testis (C and D), whereas all the mutant individuals were undergoing or had completed ovary-testis transformation with typical testicular tissues containing different stages of spermatogenic cells. Some individuals (E–H) still contained a few typical EPOs (asterisks) scattered among the testicular tissues. Arrows indicate the apoptotic germ cells.

Expression Data

Expression Detail

No data available

Antibody Labeling

Phenotype Data

Fish:	cyp19a1a^umo5/umo5; zf45Tg/+ (AB)
Observed In:	female gonad development
Stage:	Days 30-44

Phenotype Detail

Acknowledgments

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