ZFIN ID: ZDB-FIG-161207-12
Powis et al., 2016 - Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. JCI insight   1:e87908 Full text @ JCI Insight
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-15 to Protruding-mouth

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
smn1 Ab3-smn1 AB control Long-pec whole organism WB
Ab3-smn1 AB + MO1-smn1 standard conditions Long-pec whole organism WB
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab3-ub WB AB control Long-pec whole organism
WB AB + MO1-smn1 standard conditions Long-pec whole organism
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-smn1 standard conditions Long-pec whole organism smn1 expression decreased amount, abnormal
Long-pec whole organism Ab3-ub labeling decreased amount, abnormal
ml2Tg + MO1-smn1 standard conditions Prim-15 motor neuron axon branchiness, abnormal
Prim-15 motor neuron axon morphology, abnormal
Prim-15 motor neuron axon truncated, abnormal
Protruding-mouth swimming behavior process quality, abnormal
Full text @ JCI Insight