FIGURE

Fig. 1

ID
ZDB-FIG-161027-9
Publication
Cox et al., 2016 - Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis
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Fig. 1

seph mutant zebrafish exhibit defects in organ development. (A) Schematic illustrating the nature of the seph mutant. (B) Survival of WT and homozygous seph mutant larvae over time. n = 160 larvae. (C) Morphological assessment and fluorescent imaging (lateral and ventral views) of WT and seph mutant larvae on a Tg(ela3l:GFP;fabp10a:dsRed) background by confocal tomography at 5 dpf. Liver volume: WT, 3.09e6 µm3; seph, 1.69e6 µm3. Pancreas volume: WT, 2.79e6 µm3; seph, undetectable. (Scale bar: 100 µm.) (D) Quantitative analysis of fluorescent liver area in WT and seph mutant larvae at 5 dpf. n = 16. ****P < 0.0001. (E) Quantitative analysis of fluorescent pancreas area in WT and seph mutant larvae at 5 dpf. n = 16. ****P < 0.0001.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: Day 5 to Days 14-20

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA
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