FIGURE

Fig. 7

ID
ZDB-FIG-160826-11
Publication
Prabhudesai et al., 2016 - LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation
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Fig. 7

Decreased LRRK2 level affects the abundance of central PD associated proteins. A: Western blot analysis of protein lysates from 3-dpf wt and LRRK2 morphant embryos using antibodies for β-synuclein, SOD1, and PARK13. LRRK2 knockdown causes upregulation of β-synuclein, SOD1, and PARK13. Both actin and GAPDH were used as loading controls. B: Quantification of the Western blot analysis against the GAPDH control. n = 3 for all groups, 12 embryos in each group in each experiment. *P < 0.05, **P < 0.01

Expression Data
Gene:
Antibodies:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neurosci. Res.
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