Fig. 1
- ID
- ZDB-FIG-150616-25
- Publication
- Zhang et al., 2015 - Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine
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Morphology and larval locomotor activity of scn1Lab ATG morphants. (A) Dorsal view of a representative 5 dpf CTRL MO-injected larva. (B) Dorsal view of a representative 5 dpf ATG MO-injected larva. (C) The y-axis depicts the total larval locomotor activity of ATG MO- compared to CTRL MO-injected larvae over a one-hour tracking experiment (30-minute integration time). Data were pooled from three independent experiments with 12 larvae per injection condition. Statistical analysis was performed using Mann-Whitney test. Error bars on all graphs represent the standard error of mean (SEM). *** P d 0.001. |
Fish: | |
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Knockdown Reagent: | |
Observed In: | |
Stage Range: | Protruding-mouth to Days 7-13 |