FIGURE

Fig. 2

ID

ZDB-FIG-150330-6

Publication

Marín-Juez et al., 2015 - GLUT2-mediated glucose uptake and availability are required for embryonic brain development in zebrafish

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Fig. 2

glut2 abrogation disrupts brain development. Phenotype of embryos injected with a control morpholino (Con MO) at 24 hours post fertilization (hpf; A and B) and at 48 hpf (C), a morpholino targeting the translational start site (ATG MO) at 24 hpf (D and E), and at 48 hpf (F) and a morpholino targeting the splice acceptor between exons 5 and 6 (Splice MO) at 24 hpf (G and H) and at 48 hpf (I). Embryos injected with both morpholinos displayed a defective formation of the hindbrain that could be observed from 24 hpf onwards. Hindbrain ventricle (hbv), midbrain/hinbrain boundary (mbh), tectal ventricle (tctv), telencephalon (t).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB/TL + MO1-slc2a2 AB/TL + MO3-slc2a2
Knockdown Reagents:	MO1-slc2a2 MO3-slc2a2
Observed In:	eye fourth ventricle fourth ventricle development hindbrain midbrain-hindbrain boundary development telencephalon
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cereb. Blood Flow Metab.