FIGURE

Fig. S4

ID

ZDB-FIG-140325-21

Publication

Wang et al., 2014 - Notch3 establishes brain vascular integrity by regulating pericyte number

Other Figures

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Fig. S4

Vascular morphogenesis and brain notch3 expression in notch3^fh332 mutants. (A,B) fli1:EGFP transgenic reporter expression showing trunk vessels in 72 hpf wild-type and notch3^fh332 mutant larvae. (C) Quantification of vessel branch points in the brain of notch3^fh332 mutant and wild-type larvae. (D,E) Fluorescent ISH showing notch3 expression in the hindbrain. Pericyte notch3 expression was largely depleted in the mutant. Arrowheads, notch3+ pericytes. *P<0.01 by Student’s 2-tailed t test. Scale bar, 200 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	notch3^fh332/fh332
Observed In:	cranial blood vessel
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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