FIGURE

Fig. 5

ID

ZDB-FIG-140304-15

Publication

Xu et al., 2014 - Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function

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Fig. 5

Cell fate specification appears normal in swap70b morphants. Un-injected and 5 ng swap70b MO1-injected embryos at 6 hpf were hybridised with various probes: Chordin, chd (A, B); goosecoid, gsc (C, D); bone morphogenetic protein 2b, bmp2b (E, F); caudal homeobox transcription factor 4, cdx4 (G, H). At tail-bud stage, the expression pattern of an anterior specific gene pax2 shifted posteriorly and became broader in Swap70b morphants, but was still in the midbrain-hindbrain boundary (I–L). Lateral views (A–J) and dorsal views (K, L) with anterior to the top are shown.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO4-swap70b
Knockdown Reagent:	MO4-swap70b
Observed In:	convergent extension involved in neural plate elongation
Stage:	Bud

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 386(1), Xu, X., Shuen, W.H., Chen, C., Goudevenou, K., Jones, P., and Sablitzky, F., Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function, 191-203, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.