ZFIN Figure: Hoffmann et al., 2013, Fig. 4

ZFIN ID: ZDB-FIG-131227-12

ZFIN ID: ZDB-FIG-131227-12

Hoffmann et al., 2013 - Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia. Basic Research in Cardiology 108(2):339 Full text @ Basic Res. Cardiol.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	WT + MO2-isl1a WT + MO2-shox2
Knockdown Reagents:	MO2-isl1a MO2-shox2
Observed In:	blood heart heart contraction pericardium regulation of heart contraction
Stage:	Protruding-mouth

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT + MO2-isl1a	standard conditions	Protruding-mouth	blood accumulation pericardium, abnormal
		Protruding-mouth	heart contraction decreased occurrence, abnormal
		Protruding-mouth	heart contraction disrupted, abnormal
		Protruding-mouth	heart decreased functionality, abnormal
		Protruding-mouth	pericardium edematous, abnormal
		Protruding-mouth	regulation of heart contraction disrupted, abnormal
WT + MO2-shox2	standard conditions	Protruding-mouth	blood accumulation pericardium, abnormal
		Protruding-mouth	heart contraction decreased occurrence, abnormal
		Protruding-mouth	heart decreased functionality, abnormal
		Protruding-mouth	pericardium edematous, abnormal
		Protruding-mouth	regulation of heart contraction disrupted, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Basic Res. Cardiol.