Fig. S9
- ID
- ZDB-FIG-131010-18
- Publication
- D'Aniello et al., 2013 - Depletion of Retinoic Acid Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases in Retinoic Acid
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Patterning of the spinal cord is affected in the RARαb1+RARαb2 deficient embryos. (A–D) Hoxb5a (spinal cord) and egr2b (rhombomeres 3+5) expression in control (n = 32), RARαb1 deficient (n = 23), RARαb2 deficient (n = 16), and RARαb1+RARαb2 deficient embryos (n = 19). (E) Measurements of the distance in arbitrary units (AU) between hoxb5a and egr2b expression. Expression of hoxb5a in the spinal cord is expanded rostrally. The rostral expansion of hoxb5a in RARαb1 deficient embryos trends similarly as RARαb2 deficient and RARαb1+RARαb2 deficient embryos, but it is not statistically significant (p = 0.06). |