FIGURE

Fig. S2

ID

ZDB-FIG-130802-26

Publication

Lancman et al., 2013 - Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb

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Fig. S2

Severe example of β-cell number reduction and disorganization in a hnf1ba^s430 mutant with mild exocrine hypoplasia. (A-D) Fluorescent confocal microscopy of Tg(ptf1a:eGFP)^jh1 (green) 3 dpf wild-type (A,B) and 10 dpf hnf1b^s430 mutant (C,D) pancreas stained for insulin to mark β-cells (red). 3D rendering showing an hnf1ba^s430 mutant at 10 dpf with a larger exocrine pancreas (C) than that of a wild type at 3 dpf (A). (B,D) Magnification (8×) of A and C showing that β-cells (red) remain both reduced and disorganized in hnf1ba^s430 mutants at 10 dpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hnf1ba^s430/s430; jh1Tg
Observed In:	pancreatic B cell type B pancreatic cell development
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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