Fig. S2
- ID
- ZDB-FIG-130624-13
- Publication
- Wang et al., 2013 - Genetic Interaction between pku300 and fbn2b Controls Endocardial Cell Proliferation and Valve Development in Zebrafish
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Both fbn2b and pku300 contribute to the formation of atrial endocardium and common cardinal vein (CCV). Compared with wild-type siblings (A), either fbn2bMO (0.4 ng) or pku300MO (4.8 ng) knockdown led to smaller percentages of morphants (16/83 by fbn2bMO; 7/81 by pku300MO) that had defects in the atrial endocardium or CCV (B, C), but simultaneous knockdown by low-dose of fbn2bMO and pku300MO resulted more morphants (49/71) that had defects in the atrial endocardium and CCV (D), suggesting a genetic interaction between fbn2b and pku300 genes. Scale bar, 50 μm. |