FIGURE

Fig. 5

ID

ZDB-FIG-130618-9

Publication

Grotek et al., 2013 - Notch signaling coordinates cellular proliferation with differentiation during zebrafish fin regeneration

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Fig. 5

NICD overexpression causes expansion of proximal mesenchymal and epidermal compartments. (A,B) Whole-mount in situ hybridization of hs:Gal4; UAS:NICD and UAS:NICD fins heatshocked repeatedly from 0 hpa to 6 dpa with the indicated markers reveals massive proximal expansion of proximal, but not distal, blastemal and epidermal domains upon NICD overexpression. mps1=6/6 fins; ilf2=6/6; and1=9/11; lef1=7/7; wnt10a and inhbaa=4/5; wnt5b and pea3=5/6. Arrowheads indicate the amputation plane. Scale bars: whole mounts, 200 μm; sections, 100 μm.

Expression Data

Genes:	and1 etv4 ilf2 inhbaa lef1 msx2b ttk wnt5b wnt10a (all 9)
Fish:	kca3Tg kca3Tg; kca4Tg
Condition:	heat shock, physical alteration: anatomical structure
Anatomical Term:	blastema
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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