FIGURE

Fig. 2

ID
ZDB-FIG-130503-39
Publication
Yuan et al., 2013 - A Novel PEGylated Liposome-Encapsulated SANT75 Suppresses Tumor Growth through Inhibiting Hedgehog Signaling Pathway
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Fig. 2

Characterization. Of liposomal SANT75 in Shh-light2 cell and transgenic zebrafish assays.

(A) Inhibition of Hh activation by liposomal SANT75 and free SANT75 in SHh-light2 cells. IC50s for both are approximately 5 nM. (B) Inhibition of Hh activity in vivo by liposomal SANT75 and free SANT75 using Gli-GFP reporter in transgenic zebrafish embryos. (C) Inhibition of inter-segmental blood vessel by liposomal SANT75 and free SANT75 in Flk-GFP transgenic zebrafish embryos.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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