FIGURE

Fig. 1

ID
ZDB-FIG-130318-10
Publication
Lu et al., 2013 - Failure in closure of the anterior neural tube causes left isomerization of the zebrafish epithalamus
Other Figures
All Figure Page
Back to All Figure Page
Fig. 1

flh is expressed in embryos with an open neural tube. In (A, E) WT and (B, F) sqt mutant embryos with closed neural tubes, the pineal precursors (p, white arrowheads) form a single, oval domain that spans the dorsal midline (dotted lines) separating the left (L) and right (R) sides of the epithalamus. (C) In sqt embryos with mild open neural tube defects, the pineal precursors still span the dorsal midline of the brain, but the pineal anlage is elongated along the left–right axis. (D, G, H) In sqt and cyc; sqt embryos with a severe open neural tube phenotypes, the pineal precursors are present in two divided domains on the left and right sides of the brain. Dorsal views of the epithalamus in (A–D) live or (E–H) fixed embryos, anterior to the top. Scale bar=20 μm.

Expression Data
Genes:
Fish:
Anatomical Term:
Stage Range: 26+ somites to Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: 26+ somites to Protruding-mouth

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 374(2), Lu, P.N., Lund, C., Khuansuwan, S., Schumann, A., Harney-Tolo, M., Gamse, J.T., and Liang, J.O., Failure in closure of the anterior neural tube causes left isomerization of the zebrafish epithalamus, 333-344, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.