FIGURE

Fig. S2

ID
ZDB-FIG-130210-17
Publication
Bercier et al., 2013 - WNK1/HSN2 Mutation in Human Peripheral Neuropathy Deregulates KCC2 Expression and Posterior Lateral Line Development in Zebrafish (Danio rerio)
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Fig. S2

Motor neurons of wnk1/hsn2 knockdown embryos are not morphologically abnormal. Wnk1/hsn2 knockdown embryos expressing GFP under the HB9 promoter (Tg(mnx1:GFP) from Flanagan-Street et al., 2005) were obtained for all three AMOs conditions (A-non injected embryo, B- MO-wnk1-ATG, C- MO-hsn2-SB52, D- MO-hsn2-SB32). The primary motor neurons did not show any defects at 48hpf, which further parallels the HSANII pathology, where patients have no motor dysfunction.

Expression Data
Gene:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Long-pec

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
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