FIGURE

Fig. 4

ID
ZDB-FIG-120914-21
Publication
Gupta et al., 2012 - A Splice Site Mutation in Laminin-alpha2 Results in a Severe Muscular Dystrophy and Growth Abnormalities in Zebrafish
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Fig. 4

Lama2cl501/cl501 fish exhibit growth abnormalities.

(A & E) Histological analysis of cross-section at 7 dpf revealed smaller brain in the mutant fish in comparison to wild-type fish. (B & F) Magnified views of brains showing tightly clumped cells in the mutant brains. (C & G) Wild-type as well as mutant fish displayed well-organized cellular layers in eyes. (D & H) Magnified views of the ganglion cell layer showed tightly organized cells with reduced extracellular space between the cellular layers in mutant fish in comparison to the wild-type.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Days 7-13

Phenotype Detail
Acknowledgments
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