FIGURE

Fig. 6

ID

ZDB-FIG-120604-5

Publication

Poulain et al., 2002 - Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates endoderm specification in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Induction of endodermal marker genes induced by ectopic mezzo in wild-type embryos, MZoep mutants and casanova mutants. (A,E) animal pole views. (B-D,F-H) Side views. Embryos were injected at the 2- to 16-cell stage with 40 pg of GFP (A) or 40 pg of mezzo mRNA and examined at the shield (A,B,E,F) or at 80% epiboly (C,D,G,H) for the expression of sox17 (B,C,D,E,G,H) or casanova (F). Ectopic mezzo induces robust expression of sox17 (B,D,E) or casanova (F). These cells were typically large and scattered like the endogenous endoderm precursors; however, most of those cells remained in the epiblast. Overexpression of mezzo rescues sox17-expressing cells in MZoep (G) and weakly induces ectopic expression of sox17 in casanova (H).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development