ZFIN Figure: Adams et al., 2012, Fig. 5

ZFIN ID: ZDB-FIG-120516-6

ZFIN ID: ZDB-FIG-120516-6

Adams et al., 2012 - A meckelin-filamin A interaction mediates ciliogenesis. Human molecular genetics 21(6):1272-1286 Full text @ Hum. Mol. Genet.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Gene:	EGFP
Fish:	zf106Tg + MO1-flncb
Knockdown Reagent:	MO1-flncb
Anatomical Term:	pronephros
Stage:	Protruding-mouth

PHENOTYPE:

Fish:	WT + MO1-flncb WT + MO1-tmem67 WT + MO1-flncb + MO1-tmem67
Knockdown Reagents:	MO1-flncb MO1-tmem67
Observed In:	brain cilium assembly eye heart inner ear notochord post-vent region pronephros
Stage:	Protruding-mouth

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Antibody	Fish	Conditions	Stage	Anatomy	Assay
EGFP		zf106Tg + MO1-flncb	standard conditions	Protruding-mouth	pronephros	IFL

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT + MO1-flncb	standard conditions	Protruding-mouth	brain hydrocephalic, abnormal
		Protruding-mouth	cilium assembly decreased process quality, abnormal
		Protruding-mouth	eye malformed, abnormal
		Protruding-mouth	heart edematous, abnormal
		Protruding-mouth	inner ear malformed, abnormal
		Protruding-mouth	post-vent region malformed, abnormal
		Protruding-mouth	pronephros cystic, abnormal
WT + MO1-flncb + MO1-tmem67	standard conditions	Protruding-mouth	brain malformed, abnormal
		Protruding-mouth	cilium assembly decreased process quality, abnormal
		Protruding-mouth	eye malformed, abnormal
		Protruding-mouth	heart edematous, abnormal
		Protruding-mouth	inner ear malformed, abnormal
WT + MO1-tmem67	standard conditions	Protruding-mouth	cilium assembly decreased process quality, abnormal
		Protruding-mouth	notochord malformed, abnormal

Full text @ Hum. Mol. Genet.