FIGURE

Fig. S11

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ZDB-FIG-120508-26

Publication

Stewart et al., 2012 - Limited dedifferentiation provides replacement tissue during zebrafish fin regeneration

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Fig. S11

Comparison of epidermal cells and intra-ray fibroblasts during regeneration. (A–D, A*–D*) Whole mount epifluorescent images of a caudal fin from a Tg(dusp6:Cre-ERT2, EAB:EGFP-FlEx-mCherry) animal containing both Class 1 epidermis and Class 2 intra-ray fibroblast mosaics before amputation (A), 2 dpa (B, B*, B**), and 14 dpa (C). Both EGFP (green) and mCherry (magenta) are shown in all panels. The dashed box marked with single asterisk outlines a region of labeled epidermis shown at higher magnification in (B*) and the dashed box marked with double asterisk indicates a region of labeled intra-ray fibroblasts shown at higher magnification (B**). The dashed yellow line shows the approximate amputation site. White arrows point at mCherry⁺ epidermal cells and yellow arrows indicate mCherry-labeled fibroblasts or fibroblast-derived cells.

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Acknowledgments

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Reprinted from Developmental Biology, 365(2), Stewart, S., and Stankunas, K., Limited dedifferentiation provides replacement tissue during zebrafish fin regeneration, 339-349, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.