FIGURE

Fig. 6

ID

ZDB-FIG-120423-12

Publication

Dong et al., 2012 - Intralineage directional notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia

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Fig. 6

Clonal Knockdown of dla Reveals Intralineage Notch Signaling in Daughter Cells of Asymmetric Division(A) A schematic depicting two different modes of Notch signaling. Left view shows lateral inhibition. Right view illustrates intralineage.(B) Overview of the transplantation strategy.(C) Representative image of a single four-cell clone. Inset is the enlargement of the area highlighted by the red dashed box.(D) Representative images of two single clones in control morpholino group (top) and dla morpholino group (bottom). In control, two single four-cell clones contain one progenitor and three neuronal granddaughter cells. In the dla morpholino group, two single four-cell clones contain four neuronal granddaughter cells.(E) Quantification for (D).**p < 0.01, ***p < 0.001 versus Ctrl MO, z test.See also Figure S5.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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