FIGURE

Fig. 8

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ZDB-FIG-120315-42

Publication

Padanad et al., 2012 - Conditions that influence the response to Fgf during otic placode induction

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Fig. 8

Formation of ectopic otic vesicles following co-misexpression of Fgf8 with Pax2a or Pax8. (A–I) Lateral views (anterior to the left) of embryos at 30 hpf, following heat shock at 10 hpf. Images show live embryos (A, B, I) or fixed specimens showing expression of cldna (C, D), otx1b (E), pax2a (F), dlx3b (G), or atoh1a (H). The specimen in (I) also carries brn3c:Gfp transgene to mark sensory hair cells. Embryos heterozygous for the indicated inducible transgenes are labeled across the top of the figure. Positions of the eye, midbrain–hindbrain border (mhb), endogenous otic vesicle (ov) and ectopic otic vesicles (arrowheads) are indicated. Scale bar, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 364(1), Padanad, M.S., Bhat, N., Guo, B., and Riley, B.B., Conditions that influence the response to Fgf during otic placode induction, 1-10, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.