FIGURE

Fig. 1

ID
ZDB-FIG-120126-34
Publication
Schepis et al., 2012 - αE-catenin regulates cell-cell adhesion and membrane blebbing during zebrafish epiboly
Other Figures
(all 14)
All Figure Page
Back to All Figure Page
Fig. 1

ctnna morphants display morphological defects. (A-C) DIC images of live zebrafish embryos at the end of gastrulation. Arrow indicates yolk bulge. (D) Western blot of αE-catenin and tubulin in whole-embryo extracts at the same stages as those shown in A-C. (E,F) Lateral view images of live embryos at the mid-segmentation stage. (G,H) Images of live embryos, dorsal view. Horizontal arrow indicates somite, vertical arrow indicates notochord. (I) Percentage of embryos exhibiting epiboly delay at the end of gastrulation, as shown in B,C. Three independent experiments with n>70: *P<10–6 versus control, #P<10–5 versus rescue. ##, not significantly different from control by Student’s t-test. (J) Fraction of embryos dead or delayed by mid-segmentation, as shown in E,F. Three independent experiments, n>70 embryos. *P<10–6, # control or rescue vs morphant P<10–5. **, not significant. Error bars indicate s.d.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Bud to 10-13 somites

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.