FIGURE

Fig. 2

ID

ZDB-FIG-110909-5

Publication

Taylor et al., 2011 - Differentiated melanocyte cell division occurs in vivo and is promoted by mutations in Mitf

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Fig. 2

Visualization of the differentiation marker tyrp1-GFP during cell division. (A) Expression of tyrp1-GFP in the developing melanocyte allows for visualization of the melanocyte cytoplasm and precedes pigment formation (83.3 hpf, thin white box and inset). Continued monitoring of this cell reveals pigmentation (85.3 hpf), followed by rounding (88.7 hpf) and division (89.0 hpf). Two cells with distinct cytoplasm are visible (89.0 hpf) that migrate apart and become dendritic (93.0 hpf). (B) A single albino tyrp1-GFP cell (73.3 hpf) clearly revealed the presence of two nuclei in the same cell (73.7 hpf) prior to division (74.0 hpf).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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