FIGURE

Fig. 1

ID
ZDB-FIG-101118-22
Publication
Schuster et al., 2010 - Glial cell line-derived neurotrophic factor defines the path of developing and regenerating axons in the lateral line system of zebrafish
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Fig. 1

Innervation defects in Huc:kaede, Et20:gfp early larvae. (A) Normal pattern in a control larva at 4 dpf. Nerve branches extend to and arborize in each neuromast. Interneuromast cells deposited by the primordium between L1 and L2 (arrows) have moved ventrally ahead of the primII-derived neuromasts, LII.1 and LII.2. Interneuromast cells deposited by primII can also be observed close to the myoseptum (arrowheads). (B) Peripheral afferent axons stop at L2 (asterisk) in a 3-dpf gdnf, ret1-MO1 fish. An intercalary neuromast (IC) is beginning to develop between L2 and L3. The red fibers posterior to L2 belong to motor axons innervating the somitic muscles. (C) A higher magnification photograph to show that no nerve branch extends beyond L2, in a 4-dpf double morphant fish. (D) Nerve stop at L2 (asterisk) in a 4-dpf gdnf-MO2 fish. Intercalary neuromasts have formed on all somitic borders posterior to the nerve arrest. Anterior is Left in all panels. (Scale bar, 100 mm.)

Expression Data
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Day 4

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Day 4

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA