FIGURE

Fig. 5

ID

ZDB-FIG-101108-45

Publication

Poulton et al., 2010 - A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development

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Fig. 5

Strain-dependent penetrance of the MO-induced gitrl morphant phenotype. Embryos of the (A-D, I-L) TL and (E-H) AB* strains were injected with 10 ng of either (A-D) control 1 or (E-L) zGL1 MO. In zGL1-injected AB* embryos advancement of the blastoderm margin was delayed and incomplete (F-H), but these embryos successfully completed epiboly and survived through the segmentation period (see Fig. 3). In contrast, zGL1- injected TL embryos could not complete epiboly, and demonstrated a progressive contraction of the embryos around the yolk (J-L).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-tnfsf18 TU + MO1-tnfsf18
Knockdown Reagent:	MO1-tnfsf18
Observed In:	epiboly involved in gastrulation with mouth forming second yolk
Stage Range:	Shield to 90%-epiboly

Phenotype Detail

Acknowledgments

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