FIGURE

Fig. S7

ID

ZDB-FIG-100401-16

Publication

Christie et al., 2010 - Syk and Zap-70 function redundantly to promote angioblast migration

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Fig. S7

Syk and Zap morphants lack a thoracic duct. Angiography in wild type Tg(fli1a:EGFP)^y1 embryos shows a clear separation between the dorsal aorta and posterior cardinal vein, and the presence of the thoracic duct lacking dye between the two vessels (A, A′). Conversely, angiography in syk^LO (B, B′), zap-70^LO (C, C′), and syk^LO:zap-70^LO double morphants (D, D′) demonstrates the clear lack of a thoracic duct between the artery and vein. In syk^LO:zap-70^LO double morphants, some ISVs also appear to have restricted or lack blood flow.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO1-syk y1Tg + MO2-zap70 y1Tg + MO1-syk + MO2-zap70
Knockdown Reagents:	MO1-syk MO2-zap70
Observed In:	thoracic duct
Stage:	Day 5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 340(1), Christie, T.L., Carter, A., Rollins, E.L., and Childs, S.J., Syk and Zap-70 function redundantly to promote angioblast migration, 22-29, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.