ZFIN Figure: Moosajee et al., 2008, Fig. 8

ZFIN ID: ZDB-FIG-090828-6

ZFIN ID: ZDB-FIG-090828-6

Moosajee et al., 2008 - Translational bypass of nonsense mutations in zebrafish rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease. Human molecular genetics 17(24):3987-4000 Full text @ Hum. Mol. Genet.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	lamb1a^m189/m189
Observed In:	eye lens optic fissure pericardium retina layer formation swim bladder inflation whole organism
Stage:	Day 6

Fig. 8 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
lamb1a^m189/m189	standard conditions	Day 6	eye decreased size, abnormal
		Day 6	eye shape, abnormal
		Day 6	lens decreased size, abnormal
		Day 6	lens displaced, abnormal
		Day 6	optic fissure closure incomplete, abnormal
		Day 6	pericardium edematous, abnormal
		Day 6	retina layer formation disrupted, abnormal
		Day 6	swim bladder inflation arrested, abnormal
		Day 6	whole organism decreased length, abnormal

Full text @ Hum. Mol. Genet.